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产品目录

重组猪IL-2图片
产品货号:
GS4899
中文名称:
重组猪IL-2
英文名称:
Recombinant Porcine Interleukin-2
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 15.2kDa,a single non-glycosylated polypeptide chain containing 134 amino acids.
储存条件:冷冻(-20℃)

概述

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.It is expressed by CD4+ and CD8+ T cells,γδ T cells,B cells,dendritic cells,and eosinophils.IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response.The receptor for IL-2 consists of three subunits(55 kDa IL2Rα,75 kDa IL2Rβ,64 kDa common gamma chain γc/IL2Rγ)that are present on the cell surface in varying preformed complexes.Recombinant porcine IL-2 is a 15.3 kDa protein containing 134 amino acid residues and it shares about 72%amino acid sequence identity with mouse,human and rat IL-2.It also shares 60%and 67%acid sequence identity with rhesus macaque and equus caballus IL-2,respectively.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观Sterile Filtered White lyophilized(freeze-dried)powder.
纯度>96%by SDS-PAGE and HPLC analyses.
来源Escherichia coli.
生物活性Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.5ng/ml,corresponding to a specific activity of>2.0×106 IU/mg.
成分Lyophilized from a 0.2μmfiltered concentrated solution in 1×PBS,pH 7.4.
内毒素Less than 1 EU/ug of rPoIL-2 as determined by LAL method.
复溶We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列APTSSSTKNT KKQLEPLLLD LQLLLKEVKN YENADLSRML TFKFYMPKQA TELKHLQCLV EELKALEGVL NLGQSKNSDS ANIKESMNNI NVTVLELKGS ETSFKCEYDD ETVTAVEFLN KWITFCQSIY STLT

相关搜索:重组猪IL-2IL-2, PorcineRecombinant Porcine Interleukin-2
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